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BIOLOGY AND MEDICINE

PROGRAM

10. Lovelace Foundation

continued

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$150,000 The equipment needs at this laboratory are singly and as mixtures so that various levels of exposure can be related to effect. in support of research on the biological consequences of inhaling fission products Remote high-speed line printer, remote card reader and input and display stem for on-line computer capability and graphical output at the field laboratory

11.

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Recording densitometer for autoradiographic studies in the lung, and physiology system and pulmonary blood volume ... recording system for detecting anomalies in cardiac output, pressures in the circulatory

...

Spectrophotometer, fluorimeter, and other equipment for biochemical, radiochemical, and aerosol physics research

Michigan State University

....

$ 56,000

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140,000
This laboratory conducts a comprehensive research program in plant biology, drawing on disciplines such as biochemistry,
biophysics, genetics and microbiology, including the influence of radiations upon function and development of plants, and
requires the following equipment.

Amino acid analyzer, spectrophotometers, ultracentrifuge and other equipment for biochemical analyses

....

65,000
43,000

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32,000

Equipment for research in plant growth and development Argon laser and other equipment for analysis of biological molecules and processes 12. Oak Ridge Associated Universities 175,000 Equipment requirements at this laboratory are in support of observation and explanation of biomedical interactions of radiations with living systems, particularly in man; development and application of radioisotopes and radiation in diagnosis and therapy of human diseases.

Mass spectrometer and associated equipment for identification of synthetic or naturally
occurring compounds in clinical and hematological studies
Tomographic laminar scanner for bone, bone marrow and tumor studies

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Instruments for nuclear medicine including physiological monitoring system and computer interface equipment

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At this laboratory equipment is needed in support of research efforts affecting toxicity and metabolism of radionuclides; inhalation studies of plutonium and uranium; terrestrial ecology; dynamic balance of radionuclides in Columbia River; micrometeorology, radiation dosimetry and physics.

48,000
47,000

Inhalation exposure equipment, whole body counting equipment and other equipment for toxicity studies of plutonium and other alpha emitters X-ray generator and cobalt 60 source for radiation exposure of small and large animals

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ESR spectrometer and other equipment for molecular and cellular level studies, radiological
chemistry and radiation instruments for research and development
Environmental chambers, counting equipment, irradiation facility, multidimensional gamma
ray spectrometer, equipment for krypton 85 detection and other equipment for studies in
the land, fresh water, marine and atmospheric environments
14.
$205,000
University of Rochester ....
The equipment identified at this laboratory is necessary to pursue the research on the biological effects of radiation and radio-
active materials, physiochemical aspects of cellular function and structure, membrane biophysics, physical chemistry of bone and
body fluids, new approaches to cancer therapy, and basic problems in aerosol physics, toxicology and respiratory function.

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$ 56,000

107,000

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Scanning electron microscope for molecular and cellular level studies
Equipment for toxicity studies of radon, plutonium and other alpha emitters
Equipment for long-term studies of effects of external irradiation using dogs and other
small animals

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General purpose equipment

45,000
25,000

15.

Other AEC Laboratories

480,000

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Washington Off-Site Research

Equipment for studies conducted for AEC by off-site contractors and other government agencies.

Total Capital Equipment

New equipment and normal replacement items for laboratory and field investigations at other on-site locations, including:

University of California, Laboratory of Radiobiology

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Nevada Operations Office .......

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APPENDIX 6

REPORT TC THE JOINT COMMITTEE

ON ATOMIC ENERGY

CONGRESS OF THE UNITED STATES

Development Of The Janus Reactor
Complex For Biological Research
By The Argonne National Laboratory

Atomic Energy Commission

B-165117

BY THE COMPTROLLER GENERAL
OF THE UNITED STATES

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At the request of the Executive Director of your Committee, the General Accounting Office made a review of the development of the Janus reactor complex by the Argonne National Laboratory for use in conducting biological research for the Atomic Energy Commission. Our principal observations are summarized in the digest appearing at the beginning of the report.

A copy of this report is being sent today to the Vice Chairman of your Committee. As agreed by the staff of your Committee, copies of the report are being made available to the Atomic Energy Commission whose comments have been incorporated in the report.

We plan to make no further distribution of this report unless copies are specifically requested, and then we shall make distribution only after your agreement has been obtained or public announce. ment has been made by you concerning the contents of the report.

Sincerely yours,

Temer B. Phets

Comptroller General

of the United States

The Honorable Chet Holifield, Chairman
Joint Committee on Atomic Energy

DIGEST

CHAPTER

1

2

Contents

Page

1

INTRODUCTION

Initiation and development of the Janus
complex

LACK OF EFFECTIVE MANAGEMENT ACTION TO
PROVIDE FOR SUCCESSFUL COMPLETION OF JANUS
REACTOR COMPLEX

Problems and delays in completing Janus
reactor and research facility

Delays in obtaining safety approvals
for reactor operation

Problems affecting reactor safety

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CH

DBM

DRL

GAO

RDT

ROD

RSRC

Chicago Operations Office

Division of Biology and Medicine

Division of Reactor Licensing

General Accounting Office

Division of Reactor Development and Technology
Reactor Operations Division

Reactor Safety Review Committee

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9

9

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