Validation in Chemical MeasurementPaul De Bièvre, Helmut Günzler Springer Science & Business Media, 2005. gada 6. dec. - 168 lappuses The validation of analytical methods is based on the characterisation of a measurement procedure (selectivity, sensitivity, repeatability, reproducibility). This volume collects 31 outstanding papers on the topic, mostly published in the period 2000-2003 in the journal "Accreditation and Quality Assurance." They provide the latest understanding, and possibly the rationale why it is important to integrate the concept of validation into the standard procedures of every analytical laboratory. In addition, this anthology considers the benefits to both: the analytical laboratory and the user of the measurement results. |
No grāmatas satura
1.–5. rezultāts no 34.
3. lappuse
... analyte , whereas selectivity_plied [ 6–10 ] . Usually , linear models are preferable but , if refers to methods ... concentration of analyte in the sample and the corresponding detector response must be investi- gated . This can be done ...
... analyte , whereas selectivity_plied [ 6–10 ] . Usually , linear models are preferable but , if refers to methods ... concentration of analyte in the sample and the corresponding detector response must be investi- gated . This can be done ...
5. lappuse
... concentration levels should be analysed vary consider- ably. The Conference ... analyte peak (signal) and the amplitude between the highest and lowest point ... analyte peak. LLOQ based on standard deviation of the response from blank ...
... concentration levels should be analysed vary consider- ably. The Conference ... analyte peak (signal) and the amplitude between the highest and lowest point ... analyte peak. LLOQ based on standard deviation of the response from blank ...
6. lappuse
... quantification (ULOQ) The upper limit of quantification is the maximum analyte concentration of a sample that can be quantified with ac- ceptable precision and accuracy (bias). In general the ULOQ is identical to the concentration of ...
... quantification (ULOQ) The upper limit of quantification is the maximum analyte concentration of a sample that can be quantified with ac- ceptable precision and accuracy (bias). In general the ULOQ is identical to the concentration of ...
7. lappuse
... analyte at the theoretical maximum concentration. Therefore, absolute recoveries can usually not be determined if ... analyte and internal standard at high and low concentrations [12]. Selectivity (specificity) Ruggedness (robustness) ...
... analyte at the theoretical maximum concentration. Therefore, absolute recoveries can usually not be determined if ... analyte and internal standard at high and low concentrations [12]. Selectivity (specificity) Ruggedness (robustness) ...
8. lappuse
... analysis, as concentration ranges of analytes in toxicological sam- ples are usually much greater than in samples for phar- macokinetic studies. Homoscedasticity, a prerequisite for unweighted models, can however only be expected for ...
... analysis, as concentration ranges of analytes in toxicological sam- ples are usually much greater than in samples for phar- macokinetic studies. Homoscedasticity, a prerequisite for unweighted models, can however only be expected for ...
Saturs
1 | |
10 | |
Clinical reference materials for the validation of | 31 |
Qualification and validation of software and computer | 42 |
Validation of the uncertainty evaluation for | 63 |
Validation criteria for developing ionselective | 73 |
quality assurance | 148 |
Is the estimation of measurement uncertainty a viable | 155 |
Different approaches to legal requirements | 159 |
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Bieži izmantoti vārdi un frāzes
acceptance Accred Qual Assur accuracy Anal analysis analyte concentration analytical chemistry analytical measurement analytical method analytical procedure Anklam AOAC AOAC INTERNATIONAL application assessment bias calculated calibration curve capillary cation certified certified reference materials Chem chemical clinical components computer systems corrosion criteria CRMs defined detector determination documentation drug EURACHEM evaluation experimental factors functions Hewlett-Packard HPLC injection installation instrument interlaboratory International laboratory linearity LLOQ matrix measurement uncertainty ment meth method validation Metrology mmol/l obtained operating parameters peak performance pharmaceutical phase precision protocol qualification quality assurance quantitative quinizarin range recovery reference materials relative standard deviation reliability reproducibility requirements ruggedness testing sample scope of accreditation solution solvent red 24 solvent yellow 124 specifications Springer-Verlag standard deviation Table tainty test methods tion trueness type of tests uncer uncertainty associated uncertainty estimation vali vendor verification Waldbronn