Principles of Clinical PharmacologyArthur J. Atkinson Jr., Darrell R. Abernethy, Charles E. Daniels, Robert Dedrick, Sanford P. Markey Elsevier, 2011. gada 28. apr. - 568 lappuses This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists.
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No grāmatas satura
1.–5. rezultāts no 74.
xvii. lappuse
... Treatment and Diagnosis National Cancer Institute Rockville, MD 20852 Charles E. Daniels Skaggs School of Pharmacy and Pharmaceutical Sciences University of California, San Diego San Diego, CA 92093-0657 Shannon Decker Health Program ...
... Treatment and Diagnosis National Cancer Institute Rockville, MD 20852 Charles E. Daniels Skaggs School of Pharmacy and Pharmaceutical Sciences University of California, San Diego San Diego, CA 92093-0657 Shannon Decker Health Program ...
18. lappuse
... treated with a 300-mg total daily dose, but rise to an average of 20 μg/mL when the dose is increased to 400 mg (15). This nonproportional relationship between phenytoin dose and plasma concentration complicates patient management and ...
... treated with a 300-mg total daily dose, but rise to an average of 20 μg/mL when the dose is increased to 400 mg (15). This nonproportional relationship between phenytoin dose and plasma concentration complicates patient management and ...
22. lappuse
... treatment: New methods for its control. JAMA 1927;88:2013–17. 5. Atkinson AJ Jr, Ambre JJ. Kalman and Clark's drug assay: The strategy of therapeutic drug monitoring. 2nd ed. New York: Masson; 1984. 6. Smith TW, Haber E. Digoxin ...
... treatment: New methods for its control. JAMA 1927;88:2013–17. 5. Atkinson AJ Jr, Ambre JJ. Kalman and Clark's drug assay: The strategy of therapeutic drug monitoring. 2nd ed. New York: Masson; 1984. 6. Smith TW, Haber E. Digoxin ...
59. lappuse
... treating patients with chronic renal failure finally was made possible by the development of techniques for ... treatment modality for critically ill patients with acute renal failure. Several variations of these techniques have ...
... treating patients with chronic renal failure finally was made possible by the development of techniques for ... treatment modality for critically ill patients with acute renal failure. Several variations of these techniques have ...
67. lappuse
... treatment time (t) is VUF, extracorporeal clearance of drug from plasma can be calculated as follows: CLEC = CD · VUF CP ·t (6.11) By analogy with Equation 6.6, the contribution of CLEC to total solute clearance during continuous renal ...
... treatment time (t) is VUF, extracorporeal clearance of drug from plasma can be calculated as follows: CLEC = CD · VUF CP ·t (6.11) By analogy with Equation 6.6, the contribution of CLEC to total solute clearance during continuous renal ...
Saturs
1 | |
9 | |
DRUG METABOLISM AND TRANSPORT | 141 |
ASSESSMENT OF DRUG EFFECTS | 273 |
OPTIMIZING AND EVALUATING PATIENT THERAPHY | 323 |
DRUG DISCOVERY AND DEVELOPMENT | 421 |
APPENDIX I Abbreviated Tables of Laplace Transforms | 527 |
APPENDIX II Answers to Study Problems | 529 |
Index | 537 |
Citi izdevumi - Skatīt visu
Principles of Clinical Pharmacology Arthur J. Atkinson Jr.,Arthur J. Atkinson Ierobežota priekšskatīšana - 2001 |
Principles of Clinical Pharmacology Arthur J. Atkinson Jr.,Charles E. Daniels,Robert Dedrick,Charles V. Grudzinskas,Sanford P. Markey Priekšskatījums nav pieejams - 2001 |
Bieži izmantoti vārdi un frāzes
absorption acid activity addition administration adverse agents analysis approach binding blood body cancer cause cells changes Chapter clearance Clin Pharmacol Ther clinical compartment compounds concentration decrease described determined differences digoxin disease distribution dose drug development effect elimination enzyme Equation errors estimate et al evaluation example expression factor Figure flow function gene half-life hepatic human identified important increased individuals infusion inhibition inhibitors initial interactions kinetics levels liver measured mechanism medication metabolism metabolites methods molecular needed normal observed occur oral organic P-glycoprotein parameters patients pharmacokinetics pharmacology Phase plasma population potential predicted pregnancy protein reactions receptor reduced relationship relative renal reported response result risk selection shown specific studies substrate Table therapeutic therapy tion tissue toxicity transport treated treatment trials tumor volume women
Populāri fragmenti
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