Principles of Clinical PharmacologyArthur J. Atkinson Jr., Darrell R. Abernethy, Charles E. Daniels, Robert Dedrick, Sanford P. Markey Elsevier, 2011. gada 28. apr. - 568 lappuses This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists.
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No grāmatas satura
1.–5. rezultāts no 82.
vi. lappuse
... Approaches to Pharmacokinetic Analysis DAVID M. FOSTER Introduction 89 Kinetics, Pharmacokinetics, and Pharmacokinetic Parameters 90 Kinetics and the Link to Mathematics 90 Pharmacokinetic Parameters 91 Noncompartmental Analysis 92 ...
... Approaches to Pharmacokinetic Analysis DAVID M. FOSTER Introduction 89 Kinetics, Pharmacokinetics, and Pharmacokinetic Parameters 90 Kinetics and the Link to Mathematics 90 Pharmacokinetic Parameters 91 Noncompartmental Analysis 92 ...
2. lappuse
... approach: 1. Inappropriate polypharmacy. 2. Failure of prescribing physicians to establish and adhere to clear therapeutic goals. 3. Failure of medical personnel to attribute new symptoms or changes in laboratory test results to drug ...
... approach: 1. Inappropriate polypharmacy. 2. Failure of prescribing physicians to establish and adhere to clear therapeutic goals. 3. Failure of medical personnel to attribute new symptoms or changes in laboratory test results to drug ...
7. lappuse
... approach to medication use. In: Cousins DM, ed. Medication use. Oakbrook Terrace, IL: Joint Commission on Accreditation of Healthcare Organizations; 1998. p. 5–17. 29. Smith SA. Estimation of glomerular filtration rate from the serum ...
... approach to medication use. In: Cousins DM, ed. Medication use. Oakbrook Terrace, IL: Joint Commission on Accreditation of Healthcare Organizations; 1998. p. 5–17. 29. Smith SA. Estimation of glomerular filtration rate from the serum ...
11. lappuse
... approach to drug dosing has been termed the target concentration strategy. The rationale of therapeutic drug monitoring was first elucidated over 75 years ago when Otto Wuth recommended monitoring bromide levels in patients treated with ...
... approach to drug dosing has been termed the target concentration strategy. The rationale of therapeutic drug monitoring was first elucidated over 75 years ago when Otto Wuth recommended monitoring bromide levels in patients treated with ...
26. lappuse
... approach to predict drug distribution volume in humans in order to evaluate its utility in compound optimization and selection during the early stages of drug development. Although this approach would not be expected to provide an ...
... approach to predict drug distribution volume in humans in order to evaluate its utility in compound optimization and selection during the early stages of drug development. Although this approach would not be expected to provide an ...
Saturs
1 | |
9 | |
DRUG METABOLISM AND TRANSPORT | 141 |
ASSESSMENT OF DRUG EFFECTS | 273 |
OPTIMIZING AND EVALUATING PATIENT THERAPHY | 323 |
DRUG DISCOVERY AND DEVELOPMENT | 421 |
APPENDIX I Abbreviated Tables of Laplace Transforms | 527 |
APPENDIX II Answers to Study Problems | 529 |
Index | 537 |
Citi izdevumi - Skatīt visu
Principles of Clinical Pharmacology Arthur J. Atkinson Jr.,Arthur J. Atkinson Ierobežota priekšskatīšana - 2001 |
Principles of Clinical Pharmacology Arthur J. Atkinson Jr.,Charles E. Daniels,Robert Dedrick,Charles V. Grudzinskas,Sanford P. Markey Priekšskatījums nav pieejams - 2001 |
Bieži izmantoti vārdi un frāzes
absorption acid activity addition administration adverse agents analysis approach binding blood body cancer cause cells changes Chapter clearance Clin Pharmacol Ther clinical compartment compounds concentration decrease described determined differences digoxin disease distribution dose drug development effect elimination enzyme Equation errors estimate et al evaluation example expression factor Figure flow function gene half-life hepatic human identified important increased individuals infusion inhibition inhibitors initial interactions kinetics levels liver measured mechanism medication metabolism metabolites methods molecular needed normal observed occur oral organic P-glycoprotein parameters patients pharmacokinetics pharmacology Phase plasma population potential predicted pregnancy protein reactions receptor reduced relationship relative renal reported response result risk selection shown specific studies substrate Table therapeutic therapy tion tissue toxicity transport treated treatment trials tumor volume women
Populāri fragmenti
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