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" Drug design by machine learning: The use of inductive logic programming to model the structure-activity relationships of trimethoprim analogues binding to dihydrofolate reductase. "
Pattern Recognition and Neural Networks - 373. lappuse
autors: Brian D. Ripley - 1996 - 403 lapas
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3D QSAR in Drug Design: Volume 1: Theory Methods and Applications

Hugo Kubinyi - 1993 - 796 lapas
...molecules, I. Med. Chem., 36(1993)811—814. 110. King, RD., Muggleton, S., Lewis, RA and Sternberg, MJE, Drug design by machine learning: The use of inductive...programming to model the structure-activity relationships of tnmethopnim analogues binding to dihydrofolate reductase, Proc. Natl. Acad. Sci. USA, 89(1992) 11322—11326....
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Foundations of Inductive Logic Programming

Shan-Hwei Nienhuys-Cheng, Ronald de Wolf - 1997 - 440 lapas
...programming. In [Wro94], pages 97-105. [KMLS92] RD King, S. Muggleton, RA Lewis, and MJE Sternberg. Drug design by machine learning: The use of inductive...logic programming to model the structure-activity relationship of trimethoprim analogues binding to dihydrofolate reductase. In Proceedings of the National...
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Logic Programming: Proceedings of the 1998 Joint International Conference ...

Joxan Jaffar - 1998 - 388 lapas
...regression. Machine Learning, 26(2/3): 147-176, 1997. [17] RD King, S. Muggleton, R. Lewis, MJE Sternberg. Drug design by machine learning: The use of inductive...of trimethoprim analogues binding to dihydrofolate reducíase. Proc. of the National Academy of Sciences of the USA 89(23): 11322-11326, 1992. [18] M....
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Quantitative Molecular Pharmacology and Informatics in Drug Discovery

Michael Lutz, Terry Kenakin - 2000 - 438 lapas
...the search for kinase inhibitors. Science 281: 533-538. King R, Muggleton S, Lewis R and Sternberg M (1992) Drug design by machine learning: the use of...structure-activity relationships of trimethoprim analogues to dihydrofolate reducíase. Proc Nati Acad Sci USA 89: 11322-11326. King R, Muggleton S, Srinivasan...
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Logic-Based Artificial Intelligence

Jack Minker - 2000 - 640 lapas
...1446, pages 165174, Berlin. Springer-Verlag. King, R., Muggleton, S., Lewis, R., and Sternberg, M. (1992). Drug design by machine learning: The use of...reductase. Proceedings of the National Academy of Sciences, 89(23):11322-11326. King, R., Muggleton, S., Srinivasan, A., and Sternberg, M. (1996). Structureactivity...
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Knowledge Discovery in Databases: PKDD 2003: 7th European Conference on ...

Nada Lavrač, Dragan Gamberger, Hendrik Blockeel, Ljupco Todorovski - 2003 - 525 lapas
...Pharmacology and Therapeuthics, 84(2): 179-191, 1999. 15. RD King, S. Muggleton, R. Lewis, and MJE Sternberg. Drug design by machine learning: The use of inductive...reductase. Proceedings of the National Academy of Sciences of the USA, 89(23):11322-11326, 1992. 16. RD King, S. Muggleton, A. Srinivasan, and MJE Sternberg....
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Protein Structure: Determination, Analysis, and Applications for Drug Discovery

Daniel Chasman - 2003 - 634 lapas
...Biology, Halkidiki, Greece, 1997, pp 198-201. 108. King, RD, S. Muggleton, RA Lewis, and MJE Sternberg. Drug design by machine learning: the use of inductive...trimethoprim analogues binding to dihydrofolate reductase. Proc. Natl. Acad. Sci. USA 89:11322-11326, 1992. 109. Muggleton, S., RD King, and MJE Sternberg. Protein...
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Il Neurologo E Internet: Manuale Di Accesso Alla Rete Con Una Selezione Di ...

G. Comi, R. Bassi, Michele M. Ciulla, F. D'alpa, F. Sicurello - 2003 - 128 lapas
...invisible computer. MAMII Press, Cambridge 16. King RD, Muggketon S. Lewis RA. Sternherg MJ ( 1 992) Drug design by machine learning: the use of inductive...logic programming to model the structure-activity. Proc Nati Acad Sci 89:11322-11326 17. Coiera E (1999) Guida all'Informatica Medica - Internet e telemedicina....
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Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function ...

George G. Harrigan, Royston Goodacre - 2003 - 354 lapas
...biotransformations. Trends Biotechnol 4: l37-l42 (l986). King RD, Muggleton S, Lewis RA, Stetnberg MJE. Drug design by machine learning - the use of inductive logic programming to model the structure-activity-relationships of lt imethoprim analogs binding to dihydrofolate-reductase. Proc...
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Knowledge Discovery in Databases: PKDD 2005: 9th European Conference on ...

Alípio Jorge, Luís Torgo, Pavel Brazdil, Rui Camacho, João Gama - 2005 - 738 lapas
...genomic data. Science, 302(5644) :449453, 2003. 14. R. King, S. Muggleton, RA Lewis, and MJ Sternberg. Drug design by machine learning: the use of inductive...trimethoprim analogues binding to dihydrofolate reductase. In Proc. Natl. Acad. Sci., pages 11322-11326, 1992. 15. R. King, S. Muggleton, A. Srinivasan, and MJ...
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